A sweetener used in soda, cakes, biscuits and ice cream slowly develops a likely fatal liver disease in children, new researchers warn.
Fructose is the deadliest form of sugar and is far more disadvantageous to health than glucose. Scientists can now tell why this is so.
It triggers an early form of fatty liver disease in the young ones, a state normally associated with alcoholics, which can develop into cancer, stroke and heart-related problems. The illness is a growing Issue, with one of four children now clinically obese by the time they are 15.
The first author, Dr. Samir Softic, of Joslin Diabetes Center in Boston, said “the disease is much more worrisome in a child of age 13, who goes from normal liver to fatty liver to liver inflammation over the span of 7 years than in someone who has been overweight for 30years.
Kids eat more sugar than adults, so fructose is a risk factor in children, which will increase their years of poor health. High-fructose corn syrup is used in sweetened beverage and many other processed foods. They are found naturally in fruits but manufacturers extract them and then take out the fiber content and nutrients to give an instant sugar rush when consumed. Experiments show mice fed fructose suffer much more metabolic distress than those given similar calories of glucose, another component of table sugar.Study published in the journal of clinical investigation, the animals were given either regular or high- fat diet and drank either plain water or water sweetened with fructose or glucose. After 10 weeks, none of the animals on a regular diet developed insulin resistance, a key factor in metabolic. Although they both gained a substantial amount of weight.
A study published in the journal of clinical investigation, the animals were given either regular or high- fat diet and drank either plain water or water sweetened with fructose or glucose. After 10 weeks, none of the animals on a regular diet developed insulin resistance, a key factor in metabolic. Although they both gained a substantial amount of weight.
Among the mice, a significant difference was seen between those drinking fructose and those taking glucose. Dr. Softic said fructose was associated with worse metabolic outcomes. The mice on a high- fat diet become more obese and more insulin-resistant compared to others on glucose diet. Both groups of animals gained fat to their livers but with different compositions.
Co-author professor Ronald Kahn explained that in comparing the 6 diets they got a much more precise way of saying “what is the role of fructose versus glucose in diet and how bad it is when it is added to a normal diet versus diet high in fat”
The research also discovered production of an enzyme called KhK, required for the first step of fructose metabolism, was in an increase in the livers of the mice who drank fructose.